By Oliver Werz, Jenny Klemm, Olof Rådmark, Bengt Samuelsson (auth.), Bengt Samuelsson, R. Paoletti, Giancarlo C. Folco, E. Granström, S. Nicosia (eds.)
This quantity is the complaints of the eleventh overseas convention on Advances in Prostaglandin and Leukotriene examine: uncomplicated technology and New scientific purposes, held in Florence, Italy, on June 4-8, 2000, which maintains the culture of overlaying either simple and scientific elements of prostaglandin and leukotriene examine.
At this assembly specific emphasis was once given to the aptitude software of the unconventional COX-2 inhibitors, the genetics of bronchial asthma in terms of the construction of leukotrienes, and novel mobile networks for the creation of leukotrienes and lipoxins.
Traditionally, as has been performed in earlier conferences of this sequence, a large amount of new fabric was once awarded and mentioned this 12 months, with specific consciousness given to the latest scientific data.
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Extra resources for Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications
Pouliot M, McDonald P, Krump E, et. al. Colocalization of cytosolic phospholipase A z, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils. Eur J Biochem 1996;238:250-58. Penrose J, Spector J, Lam B, et. al. Purification of human lung LTC 4 synthase and preparation ofa polyclonal antibody. Am J Respir Crit Care Med 1995;152:283-89. Srere P. Complexes of sequential metabolic enzymes. Annu Rev Biochem 1987;56:89124. Brock TG, Paine R, Peters-Golden M.
Biological actions ofthe free acid ofhepoxilin A3 on human neutrophils. Bioehern Pharmacol 1999;59:435-40. Margalit A, Sofer Y, Grossrnan S, Reynaud D, Pace-Asciak CR, Livne AA. Hepoxilin A 3 is the endogenous lipid mediator opposing hypotonie swelling of intact human platelets. Proc Natl Acad Sei USA 1993;90:2589-92. TRANSCRIPTIONAL REGULATION OF THE HUMAN LEUKOTRIENE C 4 SVNTHASE PROMOTER Ji-liang Zhao, K. Frank Austen, and Bing K. Lam The cysteinylleukotrienes are a class of molecules originally known as the slow-reacting substances of anaphylaxis (SRS-A).
Localization of functional prostaglandin Ez receptors EP 3 and EP4 in the nuclear envelope. J Biol Chem 1999;274: 15 28. 29. 15719-24. Bhattaeharya M, Peri K, Almazan G, et. al. Nuclear loealization of prostagiandin E2 reeeptors. Proe Natl Aead Sei USA 1998;95:15792-97. Provost P, Samuelsson B, Radmark O. Interaetion of5-lipoxygenase with eellular proteins. Proe Natl Aead Sei USA 1999;96: 1881-85. CALCIUM BINDING SITE OF 5-LIPOXYGENASE Tove Hamrnarberg, Patrick Provost, Konda Veera Reddy, Bengt Persson, and 0 lof Rädmark 5-lipoxygenase (5LO) catalyzes the formation of leukotriene A4 from arachidonic acid.
Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications by Oliver Werz, Jenny Klemm, Olof Rådmark, Bengt Samuelsson (auth.), Bengt Samuelsson, R. Paoletti, Giancarlo C. Folco, E. Granström, S. Nicosia (eds.)